HOUSTON (Oct. 17, 2005) – The gene responsible for Rett syndrome, a devastating neurological disease found mostly in girls, not only silences some genes but in combination with another also regulates ...

Viral-infected cell lines are a commonly used experimental system to investigate host mechanisms and restriction factors, which inhibit viral replication and infection. In the present study, ...

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, ...

The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

The genetic code for the human brain is much more complex than we realised, with some genes potentially encoding tens or even hundreds of different proteins. The finding comes from the first ...

The eukaryotic spliceosome is a multi-megadalton ribonucleoprotein (RNP) complex found in eukaryotic nuclei that catalyzes the removal of introns (non-coding regions) from pre-mRNA and splices exons ...

Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

The predicted protein structure of FNBP1, one of the potential cancer-driving genes. The study predicts that inclusion of the exon (in yellow) helps cancer cells grow and spread. Researchers at the ...