In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...

Amidation reactions are the most common reactions in the chemical industry. They are indispensable for a wide range of industrial production processes, but their ecological footprint is highly ...

Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...

Figure 1: Selective amidation reaction using newly designed iridium (Ir) catalysts. Abundant in nature Hydrocarbons are used as substrates to synthesize nitrogen-containing ring, called gamma-lactams.

A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...

Researchers employed the gold electrode and attached the target molecules onto the electrode. Just like functional groups generate diverse electronic effects, one electrode fits all reactions as the ...

DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...

• Freiburg chemist Dr Tobias Schnitzer receives €1.5 million from the Vector Foundation to develop sustainable amidation reactions. • These reactions do not require toxic reagents and are highly ...