Flash column chromatography was developed in 1978 as an alternative method to long column chromatography. The method aims to isolate a component from a mixture and thereby purify it. It was built from ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

What is 2D liquid chromatography? Two-dimensional (2D) liquid chromatography is a powerful tool to separate complex compound mixtures. The principle behind 2D liquid chromatography is that compounds ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Therapeutic drug monitoring (TDM) for evaluating drug concentrations in patient serum samples is an effective method in pharmacological therapy 1. Drug administration rate is not directly reflected by ...

Controlling chromatography systems for downstream processing of biotherapeutics is challenging because of the highly nonlinear behavior of feed components and complex interactions with binding phases.