Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases. This ...

Using robots and click chemistry, scientists built potential active ingredients for future antibiotics that contain metal.

Recent advances in the study of bioactive compounds have yielded a plethora of synthetic and natural molecules that exhibit potent antiproliferative activity. These compounds, ranging from ...

Honghui Hu of Wanhuida Intellectual Property considers the impact of the structure-activity relationship on the inventiveness assessment of pharmaceutical compounds Bayer Intellectual Property GmbH ...

Recent successes of immunomodulatory approaches for the treatment of serious diseases such as cancer have generated a significant growth in efforts aimed at the discovery of novel therapeutics in this ...

Scientists have identified lucidenic acid A, one of the bioactive compounds of Ganoderma lucidum, as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) host cell ...

Clinical failure in the pharmaceutical industry remains at a staggering 90%. Failed drugs are costly, both financially and in terms of human suffering. The debate rages on about how best to fix the ...

Announcing a new publication for Acta Materia Medica journal. Sodium-glucose cotransporter 2 inhibitors are a class of glucose-lowering drugs known for robust cardiovascular protective properties.