Most of the cells in our body carry the genome, and those cells are constantly bombarded with environmental influences including UV rays, pollution, alcohol, and other exposures that can damage the ...

A research team led by Professor ZHAO Guoping at the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has unveiled a crucial mechanism that helps regulate DNA damage repair, ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

Poly(ADP‐ribose) polymerases (PARPs) are a family of enzymes that play a crucial role in maintaining genomic integrity by detecting DNA damage and facilitating its repair. By catalysing the covalent ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Deinococcus radiodurans is renowned for its extraordinary resistance to ionising radiation and other environmental stresses. This bacterium employs a combination of passive and active mechanisms to ...

Scientists have identified a mechanism that cells use to repair damage in DNA that is associated with aging and health conditions like cancer and ALS (also known as motor neuron disease). In this ...

A group of nerve cells essential for cognition may be especially vulnerable to DNA damage upon exposure to inflammation in MS.

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is ...

A recent study in Nature Communications examined how RNA polymerase I (Pol I) responds to abasic (Ap) site formation—the most common type of DNA damage. The researchers found that Pol I helps maintain ...

CPD, a biotechnology-derived active based on an Antarctic scientific discovery. Developed for topical use, it supports DNA ...