RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...

Fully cell-free process aims to further democratize personalized cancer therapeutic manufacturing with shorter turnaround times and negligible bioburden and endotoxin risks. As late-stage PCT clinical ...

Insights could not only pave the way for new treatment strategies for genetic disorders, cancer and neurodegenerative diseases, but also enhance gene-editing technologies.

RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...

Elegen and Nutcracker Therapeutics launched a pilot program to demonstrate what they label the industry’s first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer ...

Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...

Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot ...