In this interview, Karl Box shows how particle drift analysis with flux techniques enhances oral drug absorption in pharmaceutical research. Can you tell us about Pion’s Rainbow Dynamic Dissolution ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

The Pharmacology Consult column will periodically review basic principles of pharmacology and drug therapy management. Such reviews may be beneficial reminders of why recommendations for specific drug ...

Advanced solutions are improving drug dissolution, absorption, and overall therapeutic performance. Drug solubility directly impacts bioavailability and absorption levels, and thus efficacy and safety ...

Nanosuspension formulation technology has evolved to meet the needs posed by the numerous water-insoluble drug candidates emerging from high-throughput drug screening programmes that emphasize fit ...

Highly potent but poorly water-soluble drug (PWSD) candidates are common outcomes of contemporary drug discovery programmes. These lipophilic compounds often exhibit poor systemic exposure following ...

Surface plasmon resonance (SPR) detectors monitor molecular interactions without labels and in real time. SPR imaging (SPRi) has the additional advantage of increased throughput since it monitors ...

an active pharmaceutical ingredient is the active ingredient contained in a drug and it is the basic material with the desired pharmaceutical properties. Active pharmaceutical ingredients play core ...

SUSTAINED-release products have been designed to contain in one dosage form the equivalent of several single doses of a drug, which is released to the body over an extended period. This slow release ...

This webinar introduces a dissolution−permeation model that describes particle dissolution within the concentration boundary layer adjacent to a semipermeable surface. Control of particle size is ...

There exists a unique and clinically relevant time course of urinary drug delivery for a loop diuretic at which the natriuretic response is optimized. This rate of drug delivery resides on the steep ...