I've used Perl/Tk in the past and while it works, the look and feel is really that of a late 90s app. There isn't much customization you can do (in terms of skinning the default Tk widgets), so ...
Qt Jambi is a new and noteworthy alternative to Swing and Java 2D for developing rich, cross-platform desktop-application interfaces. In this article JavaWorld contributor Jeff Hanson introduces the ...
RealBasic is a tool I have used to build GUI wrappers around my shell scripts. It can do what you want but it is not free at $99 for the Mac only version.
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