A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

Chemical-genetic interaction profiling harnesses the genetic tractability of fungal models to map systematically how small molecules perturb cellular networks. By exposing collections of gene deletion ...

There are individuals who carry the same deletion of chromosome 16, and those same delections can lead to a wide range of potential neurodevelopmental issues in carriers, from milder mental illnesses ...

Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in ...

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

A new study indicates a common genetic variant may interact with gut bacteria to trigger chronic inflammation in ulcerative colitis. The findings may help explain why people experience the disease ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

This study is led by Professors Huihui Li (Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China), Liang Li (Institute of Crop Sciences, Chinese Academy of Agricultural ...