Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...
The involvement of glial cells in Alzheimer's disease (AD) has been mostly viewed as a secondary adaptive response to ...
The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...
Enhanced glucose uptake in glial cells might help fight AD. In Alzheimer’s disease and related neurodegenerative diseases, excess activation of glial cells causes neuroinflammation and damage to ...
Researchers from Tokyo Metropolitan University have discovered that impaired glucose metabolism in glial cells, a type of cell in our nervous system, plays a key role in the degeneration caused by ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...
Homeostasis is the ability of living organisms to maintain stable internal conditions, such as temperature, hydration and blood sugar levels, irrespective of any changes in their surroundings.
Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...