Researchers at Tampere University, Finland, have published new results in collaboration with an international research network that help to understand the biological phenomena mediated by cell ...

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at Vanderbilt University Medical Center have ...

The development and proper functioning of the kidney is dependent on the interaction of kidney cells with the surrounding extracellular matrix (ECM). These interactions are mediated by heterodimeric ...

Integrins are heterodimeric transmembrane receptors that mediate bidirectional communication between the extracellular matrix and intracellular signalling networks. In epithelia, they coordinate ...

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute ...

Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells attach to one another. Now a new study by Fox Chase Cancer Center researchers ...

Integrins are heterodimer transmembrane receptors for the extracellular matrix composed of an alpha and beta subunit. Natural integrin ligands include laminin, fibronectin, and vitronectin, but they ...

Protein evolution occurs slowly via small incremental mutations—usually. However, dramatic changes can happen: for instance, a fragment of one protein getting copied into the middle of another. While ...

The prognostic value of cognition in patients with glioblastoma multiforme. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a full text component.