We tested the following fluorescent dyes for their efficacy in the custom labeling reaction: amino-methyl coumarin (AMCA); diethyl aminomethyl coumarin (DEAC); Cascade Blue; fluorescein isothiocyanate ...

DNA polymerases catalyze efficient and high-fidelity DNA synthesis. While this reaction favors nucleotide incorporation, polymerases also catalyze a reverse reaction, pyrophosphorolysis, that removes ...

Nucleic acids may be labeled at their 3’ end, 5’ end, or throughout the molecule, depending on the desired application. Myriad of enzymatic or chemical methods are utilized to generate nucleic acids ...