Type 2 diabetes is characterised by chronic hyperglycaemia, which disrupts the balance between reactive oxygen species production and endogenous antioxidant defences. This oxidative stress leads to ...
Melatonin intervention linked to borderline significant increase in urinary 8-OH-dG, which is indicator of oxidative DNA damage repair capacity. (HealthDay News) — For night shift workers, melatonin ...
This compromises the body's ability to repair oxidative DNA damage, the by-product of normal cellular processes, heightening the risk of certain cancer in these workers, explain the researchers. They ...
Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...
Melatonin supplementation may help offset the DNA damage associated with night shift work by boosting the body’s ability to repair it, suggest the findings of a small clinical trial published online ...
New research shows hydroxyurea reshapes DNA replication in cancer cells, revealing stress responses that may help design ...
A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a second, equally critical function, safeguarding the integrity of human DNA.
Researchers observed a borderline statistically significant 1.8-fold increase in urinary 8-OH-dG excretion during day sleep in association with the melatonin intervention. HealthDay News — For night ...