Epidermal growth factor-dependent cyclooxygenase-2 induction in gliomas requires protein kinase C-δ
Earlier, we showed that epidermal growth factor receptor (EGFR) signaling in human glioma cells increased cyclooxygenase-2 (COX-2) expression through p38-mitogen-activated protein kinase ...
The thrombin receptor is a member of the seven transmembrane domain receptor family that can transduce mitogenic stimulation by coupling to heterotrimeric G proteins Gi and Gq, leading to inhibition ...
There is a largely arbitrary transition between ‘acute’ and ‘chronic’ pain, with temporal cut-offs after which point acute pain becomes chronic pain. Thus, an understanding of the cellular mechanisms ...
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