Reducing RAD23A levels helped nerve cells better handle toxic TDP-43 protein clumps, improving survival and function in an ALS mouse model.
Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...
A recent review article highlights evolving MS-based methodologies that are reshaping ligand discovery and mechanistic characterization for membrane protein drug targets. LCGC International spoke to ...
For decades, scientists have known that a misbehaving protein sits at the heart of Parkinson’s disease, yet the precise chain of events that turns that protein into brain cell death has remained ...
Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...
The recommended target for protein intake increased from 0.8 g/kg/day to 1.2-1.6 g/kg/day in 2026. Individual protein requirements vary by age, sex, and physical activity.