Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell ...

The new CRISPR platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold ...

"DNA guides are far cheaper and easier to manufacture than RNA guides, and they are far more stable," Jain said. "While RNA molecules degrade quickly, DNA can remain intact for long periods." Together ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

Dr. Cech is a biochemist and the author of the forthcoming book “The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets,” from which this essay is adapted. See more of our coverage in your ...

The United States Food and Drug Administration has just approved the first-ever clinical trial that uses CRISPR-Cas13 RNA editing. Its aim is to treat an eye disease called wet age-related macular ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...

Plant DNA extraction is often hindered by compounds such as polyphenols, polysaccharides, and pigments that co-purify with DNA and interfere with downstream applications. These contaminants can ...

Researchers have developed the first DNA-guided CRISPR system, improving precision, stability, and cost over RNA-based ...