Determining aqueous compound solubility has become an essential tool in the early stages of the drug discovery process. Solubility of a compound is important in the Biopharmaceutics Classification ...
Researchers have developed a new method for the accurate determination of the water content of water-soluble compounds. This plays a significant role in various areas, including determining drug ...
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Gelteq preclinical study demonstrates enhanced oral delivery of oil-soluble and poorly soluble drugs using its gel-based platform
Gelteq Limited (“Gelteq” or the “Company”), a clinical and science-based developer of advanced gel-based oral delivery systems, today announced preclinical findings demonstrating the effectiveness, ...
Poor solubility remains a big issue for drug development and, as such, is driving innovation in approaches and use of novel technologies to help overcome the associated challenges. Increasingly, ...
Dedong Wu, senior scientist at AstraZeneca, explains how nanoparticle engineering and crystal engineering can aid solubility. Wu: For poorly soluble drug candidates, various enabling techniques have ...
The global polymer-based solubility enhancement excipients market was valued at approximately USD 3,618 Million in 2024. It is projected to expand significantly, reaching around USD 8,481 Million by ...
Sucralose, a widely used artificial sweetener sold under the trade name Splenda®, is metabolized in the gut, producing at least two fat-soluble compounds, according to a recent study using rats. The ...
Most of the enzymes involved in drug metabolism are present in the liver. This means the liver plays a key role in drug metabolism. Drug metabolism occurs when the body chemically alters drugs so it ...
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