This article and associated images are based on a poster originally authored by Leif, F., Hsia, O., Cowan, A.D., Iso, K. and Ciulli, A. and presented at ELRIG Drug Discovery 2025 in affiliation with ...
Targeted protein degradation has moved well beyond its prologue more than 20 years ago. 1 The number of publications describing different PROTACs (PROteolysis TArgeting Chimeras), molecular glues, and ...
A 3D virtual model of the PKMYT1–PROTAC–CRBN ternary complex depicting how Insilico Medicine’s bifunctional proteolysis-targeting chimera (PROTAC) D16-M1P2 (shown in yellow) inhibits ...
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