Abnormal centrosome numbers are detected in virtually all cancers. The molecular mechanisms that underlie centrosome amplification, however, are poorly characterized. Based on the model that each ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

This news release is available in German. The duplication of cellular contents and their distribution to two daughter cells during cell division are amongst the most fundamental features of all life ...

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

Biologists at the National University of Singapore (NUS) have uncovered how the protein NuSAP safeguards tiny structures inside cells called centrioles, revealing a mechanism linked to developmental ...

Two recent studies in Drosophila demonstrate that overexpression of proteins required for centriole duplication can not only induce centriole over-duplication in cells containing centrioles, but can ...

Investigators from the UEx have developed a methodology with new algorithms to analyze the location of the centriole in a model cell. Thanks to this technology, they have been able to discover how the ...

Scientists at Johns Hopkins say they have learned that most cells will not divide without centrioles, and they found out why. The p53 protein, already known to prevent cell division for other reasons, ...

Scientists say they have discovered critical features of cancer cells that may help clinicians better fight the disease. The researchers found that the number and size of centrioles are increased in ...

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes ...

A two-step recruitment model based on the findings for the CEP57-CEP63-CEP152 complex during a single cell cycle. (A) During S to G2 phase, CEP57 is gradually recruited to the procentriole, crucial ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...