Merck Scientists Publish Landmark Paper on Novel Method for Large-Scale Biocatalytic Synthesis of Investigational Oral PCSK9 Inhibitor, Enlicitide Decanoate

Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today the publication of work describing the ...
C&EN

Kinase inhibitors can be targeted protein degraders too

An illustration shows the structure of an inhibitor bound to the active site of membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase. An inhibitor bound to the active site of ...
AZoRobotics

AI Discovery Pipeline Identifies Tuberculosis Drug Targets

Five novel inhibitors of the MenT3 toxin were identified through a machine learning and simulations pipeline, offering new ...

Two-faced protein discovery may explain why leukemia drugs fail or succeed

A KAIST research team has identified the real reason why anticancer drugs kill cancer cells—targeted anticancer therapies do not simply block cancer proteins but rather shut down the "protein ...