Short-term nutritional state can reshape T cell metabolism, with post-meal lipid metabolism enhancing T cell metabolic ...

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

AT-108 induces powerful, personalized anti-cancer responses by forcing tumor cells to present their antigens to the immune ...

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the ...

A study showed that non-immune cells shape mRNA vaccine responses. Expression of mRNA in muscle cells increased immunity, ...

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, ...

Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and mount potent anti-tumor responses. These properties make them an attractive ...

A clinical trial to reverse age-related vision conditions using stem cell treatment could finally deliver on the promise of a ...

A stabilized mRNA carrier turns tumor injection into broader immune activation by extending vaccine delivery to lymph nodes ...

In 2021, a woman with severe lupus at University Hospital Erlangen in Germany became the first person to receive CAR-T cell ...