In biology, reprogramming refers to erasure and remodeling of epigenetic marks, such as DNA methylation, during mammalian development or in cell culture. [1] Such control is also often …

2 days ago · Reprogramming antigen-specific T cells into pluripotent stem cells with unlimited self-renewal capacity represents an innovative and powerful strategy to overcome these …

Apr 9, 2025 · This review summarizes the recent advances in cell reprogramming mediated by transcription factors or chemical molecules, followed by elaborating on the important roles of …

Jul 31, 2025 · Learn about the intricate science of cell reprogramming, a process that redefines biological possibilities for health and discovery.

6 days ago · Abstract Cellular reprogramming, a method of “resetting” the epigenetic clock by reversing the differentiation state of cells, has emerged as a promising approach to anti-aging, …

Jun 1, 2025 · Chemical reprogramming uniquely enhances the plasticity of human somatic cells, reverting them to progenitor states through dedifferentiation, thereby offering a potential …

5 days ago · Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, which are infection and tumor-fighting white blood …

Epigenetic reprogramming has shown therapeutic potential across a wide spectrum of diseases including neurodegenerative disorders, cancers, cardiovascular conditions, and metabolic …

Dec 2, 2025 · Cell reprogramming is the act of reverting mature, specialised cells into induced pluripotent stem cells, also known as iPS cells. This process requires a stem or progenitor cell …

In 2006, scientists led by Shinya Yamanaka at Kyoto University in Japan pioneered a new technology, known as induced pluripotent stem cells, or iPSC for short. This breakthrough …