In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. [1]

Aug 28, 2025 · The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats and mice.

Aug 21, 2025 · The LD50, or Lethal Dose 50%, is a standard measure in toxicology for the acute toxicity of a substance. This metric provides a quantitative estimate of a material’s short-term poisoning …

Feb 11, 2018 · The median lethal dose, or LD50, is a term used in toxicology as a measurement of a lethal dose of a substance (e.g., pathogen, medication, toxic substance, etc.). Specifically, the LD50 …

Jun 14, 2025 · LD50, or the median lethal dose, is a crucial concept in toxicology that measures the toxicity of a substance. It is defined as the dose of a substance that is lethal to 50% of the test …

Dec 3, 2025 · Understand what is LD50 and its crucial role in pharmacology and toxicology. Explore its history, calculation, ethical concerns, and modern alternatives to acute toxicity testing.

The LD50 describes the amount of chemical ingested or absorbed by the skin in test animals that causes death in 50% of test animals used during a toxicity test study.

The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill …

Aug 8, 2025 · The LD50, or Lethal Dose 50%, serves as a standard measure in toxicology for assessing a substance’s acute toxicity. It quantifies the amount of a material that is expected to cause death in …

LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD50 is one way to measure the short-term poisoning potential (acute toxicity) of …