Sortase refers to a group of prokaryotic enzymes that modify surface proteins by recognizing and cleaving a carboxyl-terminal sorting signal.

Jul 1, 2024 · Sortases are a widespread family of bacterial transpeptidases that covalently anchor proteins to the cell surface and assemble bacterial pili.

Jul 25, 2025 · Sortase A is an enzyme, a protein that accelerates specific chemical reactions within living organisms. This particular enzyme is found on the surface of certain bacteria, …

Jan 11, 2021 · Here, we describe the laboratory evolution of the bacterial transpeptidase sortase A to recognize the LMVGG sequence in endogenous amyloid-β (Aβ) protein.

Sortase enzymes are critical cysteine transpeptidases on the surface of bacteria that attach proteins to the cell wall and are involved in the construction of bacterial pili.

Sortases are membrane-bound transpeptidases that cleave the sorting signal of the secreted protein to form an isopeptide bond between the secreted protein and peptidoglycan.

Aug 4, 2021 · Site-specific protein modification is a widely-used biochemical tool. However, there are many challenges associated with the development of protein modification techniques, in …