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  1. Syphilis: Screening and diagnostic testing - UpToDate

    Aug 21, 2024 · Treponemal tests — Treponemal tests have historically been more complex and expensive to perform than nontreponemal tests. Thus, they have traditionally been used as …

  2. Syphilis - STI Treatment Guidelines

    Jan 16, 2024 · Persons with a positive treponemal screening test should have a standard quantitative nontreponemal test with titer performed reflexively by the laboratory to guide …

  3. Syphilis: Treponemal Antibodies With Reflex to RPR and RPR ... - Labcorp

    Treponemal antibody by chemiluminescent immunoassay with reflex of positive specimens to RPR. If RPR is positive, RPR titer will be performed. If RPR is negative, a second treponemal …

  4. Treponema pallidum - Syphilis | Choose the Right Test

    Two categories of serologic tests are used to diagnose syphilis: treponemal and nontreponemal tests. It's recommended that one of two testing algorithms be used: the traditional algorithm or …

  5. Treponemal tests, also called confirmatory tests (FTA, TP-PA, EIA), detect antibodies specific to syphilis. Treponemal antibodies will appear earlier after acute infection than non-treponemal …

  6. Performance of treponemal tests for the diagnosis of syphilis

    Treponemal immunoassays are increasingly used for syphilis screening with the reverse sequence algorithm. There are little data describing performance of treponemal …

  7. TPPA Test: Syphilis Diagnosis, Procedure & Accuracy Explained

    The TPPA test, formally known as the Treponema pallidum particle agglutination test, is a specialized blood test used to diagnose syphilis—a sexually transmitted infection caused by …

  8. In the past decade, laboratories throughout California have increasingly employed automated treponemal enzyme immunoassays (EIA) or chemiluminescence assays (CIA) as the initial …

  9. Syphilis Testing: Types, Timing, And Accuracy - STDcenterNY

    Nontreponemal tests are used in conjunction with other tests to diagnose syphilis. They are also used in syphilis treatment to actively follow a patient’s response to medication. Confirmatory …

  10. ongly suggests re-infection. The specific treponemal screen assay is a total antibody (IgM+IgG) assay against recombi. ant antigens of T. pallidum. They appear 2–3 weeks post infection …