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0:55
YouTube
Chemistry - CSIR NET, GATE & SET: IFAS
Hoffmann Bromide Rearrangement | Organic Chemistry | CSIR NET Chemistry | IFAS
In this Reel, IFAS Expert Faculty focuses on the Hoffmann Bromide Rearrangement reaction mechanism. Key concepts covered: Reactants: Amide + Br₂ + NaOH (base) Step 1: Base abstracts N–H proton, followed by electrophilic bromination and loss of Br⁻. Step 2: Second deprotonation by OH⁻ generates a nitrene intermediate. Step 3: Nitrene ...
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1 month ago
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